Arthritis Research & Therapy

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Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model

Jianyong Shou*, Christopher M Bull, Li Li, Hui-Rong Qian, Tao Wei, Shuang Luo, Douglas Perkins, Patricia J Solenberg, Seng-Lai Tan, Xin-Yi C Chen, Neal W Roehm, Jeffrey A Wolos and Jude E Onyia

Arthritis Research & Therapy 2006, 8:R28 doi:10.1186/ar1883

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Research article   Open Access

The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challenge

Hua Yu, Changwan Lu, Ming T Tan, Kamal D Moudgil Arthritis Research & Therapy 2011, 13:R143 (13 September 2011)

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T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis

Fang Du, Liang-jing Lü, Qiong Fu, Min Dai, Jia-lin Teng, Wei Fan, Shun-le Chen, Ping Ye, Nan Shen, Xin-fang Huang, Jie Qian, Chun-de Bao Arthritis Research & Therapy 2008, 10:R136 (19 November 2008)

T-614, a novel oral anti-rheumatic agent, effectively attenuates joint inflammation and offers significant protection against bone and cartilage destruction in an experimental model of collagen-induced arthritis.

Research article   Open Access

Developing and applying a gene functional association network for anti-angiogenic kinase inhibitor activity assessment in an angiogenesis co-culture model

Yuefeng Chen, Tao Wei, Lei Yan, Frank Lawrence, Hui-Rong Qian, Timothy P Burkholder, James J Starling, Jonathan M Yingling, Jianyong Shou BMC Genomics 2008, 9:264 (2 June 2008)

Research article   Open Access

Arthritis suppression by NADPH activation operates through an interferon-β pathway

Peter Olofsson, Annika Nerstedt, Malin Hultqvist, Elisabeth C Nilsson, Sofia Andersson, Anna Bergelin, Rikard Holmdahl BMC Biology 2007, 5:19 (9 May 2007)

In arthritis-susceptible rats, a natural alcohol, phytol, protects against arthritis by boosting NADPH oxidase via an interferon-beta associated pathway, in contrast to the interferon-gamma regulation of the immune system that drives arthritis progression.