Table 1 |
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|
Frequency distribution of the PTPN22 1858C/T polymorphism |
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| Pre-patients (n = 89) |
Controls (n = 360) |
χ2 |
P value |
OR |
95% CI |
|||
|
|
||||||||
| N |
% |
n |
% |
|||||
|
|
||||||||
| CC |
54 |
60.7 |
289 |
80.3 |
15.21 |
0.00010 |
0.38 |
0.22–0.64 |
| CT |
33 |
37.1 |
68 |
18.9 |
13.54 |
0.00025 |
2.52 |
1.48–4.30 |
| TTa |
2 |
2.2 |
3 |
0.8 |
1.30 |
0.2586 |
2.74 |
0.31–20.46 |
| CT + TT |
35 |
39.3 |
71 |
19.7 |
15.21 |
0.00010 |
2.64 |
1.56–4.47 |
| T allele |
37 |
20.8 |
74 |
10.3 |
14.55 |
0.00013 |
2.29 |
1.45–3.61 |
|
|
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|
Frequencies of PTPN22 1858C/T genotypes and of the T allele were determined in individuals who later developed rheumatoid arthritis (pre-patients) and in controls. aFisher's exact test (two-sided). CI, confidence interval; OR, odds ratio. |
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|
Johansson et al. Arthritis Research & Therapy 2006 8:R19 doi:10.1186/ar1868 |
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