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Unanswered questions about B cell therapies |
| What is the duration of clinical efficacy after a single course of rituximab? Belimumab? |
| Is there a need for concomitant corticosteroids with each course of corticosteroids? |
| What are the long-term implications of CD20+ B cell depletion? |
| Is there a risk for increased occurrence of serious infections with B cell targeted therapies? Opportunistic infections? |
| What role might biologics play in combination with B cell targeted therapies? |
Keystone Arthritis Research & Therapy 2005 7(Suppl 3):S13 doi:10.1186/ar1738 |