Table 1

Demographic and serological profiles of patients with SLE

Characteristic

SLE patients

Anti-NPM antibodies

(n = 82)

Positive (n = 23)

Negative (n = 59)


Age, years (mean ± SD)

38.3 ± 12.3

39.8 ± 14.9

37.8 ± 11.5

Females

73 (89.0)

18*

55

Males

9 (10.8)

5*

4

aCL

32 (39)

15 (65.2)**

17 (28.8)**

ANA-positive

66 (80.5)

23 (100)

43 (72.8)

Anti-DNA

46 (56)

13 (56.5)

33 (55.9)

Anti-β2GPI

15 (18.3)

5 (21.7)

10 (16.9)

Anti-β2GPI-CL+

12 (14.6)

3 (13)

9 (15.2)


aCL, anti-cardiolipin; ANA, anti-nuclear antibodies; β2GPI, β2-glycoprotein I; CL, cardiolipin; NPM, nucleophosmin; SLE, systemic lupus erythematosus. Values are n (%) unless indicated otherwise.

* χ2 = 2.4; P = 0.12. ** χ2 = 9.2; P = 0.002.

Lartigue et al. Arthritis Research & Therapy 2005 7:R1394-R1403   doi:10.1186/ar1838

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