Binding of rhNPM to cardiolipin and effects of nucleophosmin on cardiolipin-binding activity of 4B7 mAb. (a) Cardiolipin was coated on plastic plates and incubated with various concentrations of recombinant human nucleophosmin (rhNPM). (b) mAb 4B7 was incubated on cardiolipin-coated plates in the absence or presence of rhNPM. Bars represent the mean A405 of duplicate experiments and error bars represent SD.
Lartigue et al. Arthritis Research & Therapy 2005 7:R1394 doi:10.1186/ar1838