Table 2

TNF-RI A36G single nucleotide polymorphism genotype frequencies and sTNFR levels

Genotype
n (%)
sTNF-RI (pg/ml)
sTNF-RII (pg/ml)

Early RA
          AA
41 (39.8)
1,543 ± 597
4,435 ± 1,898
          AG
50 (48.5)
1,426 ± 629
4,302 ± 1,672
          GG
12 (11.7)
1,303 ± 447
4,566 ± 1,490
Established RA
          AA
48 (31.8)
1,827 ± 758
5,740 ± 1,942
          AG
70 (46.4)
1,688 ± 674
5,475 ± 2,020
          GG
33 (21.8)
1,757 ± 559
5,857 ± 2,393

Shown are tumor necrosis factor receptor I (TNF-RI) A36G single nucleotide polymorphism genotype frequencies and soluble tumor necrosis factor receptor (sTNFR) levels in rheumatoid arthritis (RA) patients with early (n = 103) and established (n = 151) disease. sTNFR levels are expressed as the mean ± standard deviation. No significant differences in sTNFR levels were found between any of the genotypes in either population. sTNF-RII, soluble tumor necrosis factor receptor II.

Glossop et al. Arthritis Research & Therapy 2005 7:R1227   doi:10.1186/ar1816

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