Table 1

Frequencies of FCGR3A and FCGR2A genotypes in patients with RA and positive and negative for anti-GPI antibodies


FCGR3A-158
FCGR2A-131



FF low
F/V
VV high
HH high
H/R
RR low

GPI+ RA (n = 23)
10 (43.5)
9 (39.1)
4 (17.4)
16 (69.6)
6 (26.1)
1 (4.3)
GPI- RA (n = 164)
86 (52.4)
68 (41.5)
10 (6.1)
128 (78)
29 (17.7)
7 (4.3)
GPI+ Control (n = 9)
8(88.9)
1 (11.1)
0 (0)
4 (44.4)
5 (55.6)
0 (0)
GPI- Control (n = 149)
83 (55.7)
58 (38.9)
8 (5.4)
109 (73.2)
40 (26.8)
0 (0)

Data are expressed as number (percentage) of individuals. GPI, glucose-6-phosphate isomerase; high, high affinity genotype; low, low affinity genotype; RA, rheumatoid arthritis.

Matsumoto et al. Arthritis Research & Therapy 2005 7:R1183   doi:10.1186/ar1802