Figure 2.

Population of anti-GPI antibody positive individuals, and FCGR3A and FCGR2A genotypes. The study included 187 patients with rheumatoid arthritis and 158 healthy Japanese individuals. The horizontal and vertical dotted lines represent the cutoff optical density values calculated from ELISA reactions of 158 healthy individuals for human recombinant GPI and rabbit native GPI, respectively. Individuals positive for both antibodies were considered anti-GPI antibody positive. Numbers in each graph represent the proportions of individuals positive for anti-GPI antibodies relative to the total number of individuals in that group. GPI, glucose-6-phosphate isomerase; HS, healthy subjects; RA, rheumatoid arthritis.