Figure 3.

Histopathological scores of the hindlimb in AIA rats fed with TM or deionized water. Mononuclear cell infiltration, pannus invasion into the cartilage and bone, and vascularity were measured by microscopic examination scores of the sections on two separate occasions (see Histological examination). We measured the scores of 16 hindlimbs (both hindlimbs of each rat). AIA, adjuvant-induced arthritis; TM, tetrathiomolybdate.