Figure 1.

Suppression of clinical arthritis by tetrathiomolybdate (TM) treatment in adjuvant-induced arthritis rats. TM was orally administered daily to female Lewis rats, from 2 weeks before immunization to day 17. TM-treated rats, 10 mg/kg/day (n = 8); control rats (n = 8). (a) Arthritis score, (b) paw volume, and (c) mean body weight were assessed every second day after onset of arthritis.