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Volume 7 Issue 6
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Comment |
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It's all in the blood: circulating endothelial progenitor cells link synovial vascularity with cardiovascular mortality in rheumatoid arthritis?
Ewa Paleolog Arthritis Research & Therapy 2005, 7:270-272 (27 October 2005)
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Gene therapy for arthritis – where do we stand?
Yuti Chernajovsky Arthritis Research & Therapy 2005, 7:227-229 (14 September 2005)
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Does a positive anti-CCP test identify a distinct arthritis entity?
Thomas Skogh Arthritis Research & Therapy 2005, 7:230-232 (16 September 2005)
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Can magnetic resonance imaging differentiate undifferentiated arthritis?
Mikkel Østergaard, Anne Duer, Kim Hørslev-Petersen Arthritis Research & Therapy 2005, 7:243-245 (13 October 2005)
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Review |
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E3 ubiquitin ligases and their control of T cell autoreactivity
Jody L Bonnevier, Ruan Zhang, Daniel L Mueller Arthritis Research & Therapy 2005, 7:233-242 (12 October 2005)
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Application of in vivo microscopy: evaluating the immune response in living animals
Clemens Scheinecker Arthritis Research & Therapy 2005, 7:246-252 (19 October 2005)
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Dipeptidyl peptidase IV activity and/or structure homologs: Contributing factors in the pathogenesis of rheumatoid arthritis?
Aleksi Sedo, Jonathan S Duke-Cohan, Eva Balaziova, Liliana R Sedova Arthritis Research & Therapy 2005, 7:253-269 (26 October 2005)
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Report |
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The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics
Christopher H Evans, Steven C Ghivizzani, Elvire Gouze, John J Rediske, Edward M Schwarz, Paul D Robbins Arthritis Research & Therapy 2005, 7:273-278 (28 October 2005)
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Research |
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Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis
Koichiro Komiya, Hiroyuki Enomoto, Isao Inoki, Satoko Okazaki, Yoshinari Fujita, Eiji Ikeda, Eiko Ohuchi, Hideo Matsumoto, Yoshiaki Toyama, Yasunori Okada Arthritis Research & Therapy 2005, 7:R1158-R1173 (5 August 2005)
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Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats
Atsushi Omoto, Yutaka Kawahito, Igor Prudovsky, Yasunori Tubouchi, Mizuho Kimura, Hidetaka Ishino, Makoto Wada, Makie Yoshida, Masataka Kohno, Rikio Yoshimura, Toshikazu Yoshikawa, Hajime Sano Arthritis Research & Therapy 2005, 7:R1174-R1182 (8 August 2005)
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A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies
Isao Matsumoto, Hua Zhang, Yoshifumi Muraki, Taichi Hayashi, Takanori Yasukochi, Yuko Kori, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida Arthritis Research & Therapy 2005, 7:R1183-R1188 (11 August 2005)
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The contact-mediated response of peripheral-blood monocytes to preactivated T cells is suppressed by serum factors in rheumatoid arthritis
Manuela Rossol, Sylke Kaltenhäuser, Roger Scholz, Holm Häntzschel, Sunna Hauschildt, Ulf Wagner Arthritis Research & Therapy 2005, 7:R1189-R1199 (17 August 2005)
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Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele
Philippe Dieudé, Sophie Garnier, Laëtitia Michou, Elisabeth Petit-Teixeira, Elodie Glikmans, Céline Pierlot, Sandra Lasbleiz, Thomas Bardin, Bernard Prum, François Cornélis, the European Consortium on Rheumatoid Arthritis Families Arthritis Research & Therapy 2005, 7:R1200-R1207 (25 August 2005)
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Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis
Bert De Klerck, Lies Geboes, Sigrid Hatse, Hilde Kelchtermans, Yves Meyvis, Kurt Vermeire, Gary Bridger, Alfons Billiau, Dominique Schols, Patrick Matthys Arthritis Research & Therapy 2005, 7:R1208-R1220 (25 August 2005)
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Absence of autoantibodies against correctly folded recombinant fibrillin-1 protein in systemic sclerosis patients
Jürgen Brinckmann, Nico Hunzelmann, Ehab El-Hallous, Thomas Krieg, Lynn Y Sakai, Sven Krengel, Dieter P Reinhardt Arthritis Research & Therapy 2005, 7:R1221-R1226 (6 September 2005)
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Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis
John R Glossop, Peter T Dawes, Nicola B Nixon, Derek L Mattey Arthritis Research & Therapy 2005, 7:R1227-R1234 (7 September 2005)
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Elimination of rheumatoid synovium in situ using a Fas ligand 'gene scalpel'
Haidi Zhang, Guangping Gao, Gilda Clayburne, H Ralph Schumacher Arthritis Research & Therapy 2005, 7:R1235-R1243 (8 September 2005)
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Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis
S Guiducci, A Del Rosso, M Cinelli, F Perfetto, R Livi, A Rossi, A Gabrielli, R Giacomelli, N Iori, G Fibbi, M Del Rosso, M Matucci Cerinic Arthritis Research & Therapy 2005, 7:R1244-R1253 (8 September 2005)
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Inflammation causes tissue-specific depletion of vitamin B6
En-Pei Chiang, Donald E Smith, Jacob Selhub, Gerard Dallal, Yi-Cheng Wang, Ronenn Roubenoff Arthritis Research & Therapy 2005, 7:R1254-R1262 (13 September 2005)
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Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b
John Dulos, Allard Kaptein, Annemieke Kavelaars, Cobi Heijnen, Annemieke Boots Arthritis Research & Therapy 2005, 7:R1271-R1280 (15 September 2005)
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Open label phase II trial of single, ascending doses of MRA in Caucasian children with severe systemic juvenile idiopathic arthritis: proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement
Patricia Woo, Nicholas Wilkinson, Anne-Marie Prieur, Taunton Southwood, Valentina Leone, Polly Livermore, Helena Wythe, David Thomson, Tadamitsu Kishimoto Arthritis Research & Therapy 2005, 7:R1281-R1288 (15 September 2005)
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Segregation of a M404V mutation of the p62/sequestosome 1 (p62/SQSTM1) gene with polyostotic Paget's disease of bone in an Italian family
Alberto Falchetti, Marco Di Stefano, Francesca Marini, Francesca Del Monte, Alessia Gozzini, Laura Masi, Annalisa Tanini, Antonietta Amedei, Annamaria Carossino, Giancarlo Isaia, Maria Brandi Arthritis Research & Therapy 2005, 7:R1289-R1295 (15 September 2005)
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Aerobic exercise and its impact on musculoskeletal pain in older adults: a 14 year prospective, longitudinal study
Bonnie Bruce, James F Fries, Deborah P Lubeck Arthritis Research & Therapy 2005, 7:R1263-R1270 (19 September 2005)
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Editor’s summary
Pain increases with age, however people who regularly carry out brisk aerobic exercise such as running, experience 25% less musculoskeletal pain in old age than those who exercise infrequently.
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Transcriptional profiles discriminate bone marrow-derived and synovium-derived mesenchymal stem cells
Farida Djouad, Claire Bony, Thomas Häupl, Gilles Uzé, Najiba Lahlou, Pascale Louis-Plence, Florence Apparailly, François Canovas, Thierry Rème, Jacques Sany, Christian Jorgensen, Danièle Noël Arthritis Research & Therapy 2005, 7:R1304-R1315 (20 September 2005)
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Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase
Robert Bockermann, David Schubert, Thomas Kamradt, Rikard Holmdahl Arthritis Research & Therapy 2005, 7:R1316-R1324 (20 September 2005)
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Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)γ agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1β-stimulated rat chondrocytes: evidence for PPARγ-independent inhibition by 15-deoxy-Δ12,14prostaglandin J2
Arnaud Bianchi, David Moulin, Sylvie Sebillaud, Meriem Koufany, Marie-Madeleine Galteau, Patrick Netter, Bernard Terlain, Jean-Yves Jouzeau Arthritis Research & Therapy 2005, 7:R1325-R1337 (22 September 2005)
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Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case–control study
Berit Sverdrup, Henrik Källberg, Camilla Bengtsson, Ingvar Lundberg, Leonid Padyukov, Lars Alfredsson, Lars Klareskog, the Epidemiological Investigation of Rheumatoid Arthritis study group Arthritis Research & Therapy 2005, 7:R1296-R1303 (23 September 2005)
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Editor’s summary
A population based case-controlled study has found that occupational exposure to mineral oils, in particular hydraulic or motor oil, increases the risk of developing rheumatoid arthritis by 30%.
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Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity
EN Blaney Davidson, A Scharstuhl, EL Vitters, PM van der Kraan, WB van den Berg Arthritis Research & Therapy 2005, 7:R1338-R1347 (30 September 2005)
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Effect of a small molecule inhibitor of nuclear factor-κB nuclear translocation in a murine model of arthritis and cultured human synovial cells
Kyoko Wakamatsu, Toshihiro Nanki, Nobuyuki Miyasaka, Kazuo Umezawa, Tetsuo Kubota Arthritis Research & Therapy 2005, 7:R1348-R1359 (30 September 2005)
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Reproducibility and sensitivity to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year interval
Emmanuel Maheu, Christian Cadet, Marc Marty, Maxime Dougados, Salah Ghabri, Isabelle Kerloch, Bernard Mazières, Tim D Spector, Eric Vignon, Michel G Lequesne Arthritis Research & Therapy 2005, 7:R1375-R1385 (5 October 2005)
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Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity
Philip L Carl, Brenda RS Temple, Philip L Cohen Arthritis Research & Therapy 2005, 7:R1360-R1374 (6 October 2005)
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The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis
Carl Turesson, Daniel J Schaid, Cornelia M Weyand, Lennart TH Jacobsson, Jörg J Goronzy, Ingemar F Petersson, Gunnar Sturfelt, Britt-Marie Nyhäll-Wåhlin, Lennart Truedsson, Sonja A Dechant, Eric L Matteson Arthritis Research & Therapy 2005, 7:R1386-R1393 (11 October 2005)
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Association between anti-nucleophosmin and anti-cardiolipin antibodies in (NZW × BXSB)F1 mice and human systemic lupus erythematosus
Aurelia Lartigue, Laurent Drouot, Fabienne Jouen, Roland Charlionet, François Tron, Danièle Gilbert Arthritis Research & Therapy 2005, 7:R1394-R1403 (13 October 2005)
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Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis
En-Pei I Chiang, Jacob Selhub, Pamela J Bagley, Gerard Dallal, Ronenn Roubenoff Arthritis Research & Therapy 2005, 7:R1404-R1411 (14 October 2005)
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Editor’s summary
Vitamin B6 supplementation corrects the observed deficiency in rheumatoid arthritis (RA) patients, and may reduce the associated risk of atherosclerosis and cardiovascular disease, but does not suppress inflammation.
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Between adaptive and innate immunity: TLR4-mediated perforin production by CD28null T-helper cells in ankylosing spondylitis
Bernd Raffeiner, Christian Dejaco, Christina Duftner, Werner Kullich, Christian Goldberger, Sandra C Vega, Michael Keller, Beatrix Grubeck-Loebenstein, Michael Schirmer Arthritis Research & Therapy 2005, 7:R1412-R1420 (18 October 2005)
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Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis
Andrew Kinloch, Verena Tatzer, Robin Wait, David Peston, Karin Lundberg, Phillipe Donatien, David Moyes, Peter C Taylor, Patrick J Venables Arthritis Research & Therapy 2005, 7:R1421-R1429 (19 October 2005)
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