Table 1

Characteristics of the PR3/MPO-ANCA-positive patients with idiopathic and antithyroid DIDs


Patients with idiopathic vasculitides (n = 56)
Patients with antithyroid DIDs (n = 16)

Female sex, n (%)
29 (52)
15 (94)*
Age, years
52.8 ± 10.9
31 ± 9.8**
Range
18–72
20–52
Months between first complaints and ANCA detection
3.8 ± 1.2
2.3 ± 1.1**
Graves' disease/Hashimoto thyroiditis, n
0
13/3
Propylthiouracil/methimazole, n
0
12/4

Values represent either numbers of patients (%) or mean ± standard deviation. *p < 0.01, **p < 0.001. ANCA, antineutrophil cytoplasmic antibodies; DID, drug-induced autoimmune disease; MPO, myeloperoxidase; PR3, proteinase 3.

Bonaci-Nikolic et al. Arthritis Research & Therapy 2005 7:R1072   doi:10.1186/ar1789

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