Table 4

TNFRII 196R allele and functional severity progression over the 1-year follow up

Whole cohort

RA patients

TNFRII 196R allele

P

TNFRII 196R allele

P

Absent (n = 132)

Present (n = 106)

Absent (n = 76)

Present (n = 80)

Baseline F-HAQ score

0.63 (0.0–2.75)

0.88 (0.0–2.50)

0.07

0.88 (0.0–2.75)

1.13 (0.0–2.50)

0.50

1-year F-HAQ score

0.46 (0.0–2.50)

0.38 (0.0–2.38)

0.78

0.63 (0.0–2.50)

0.63 (0.0–2.38)

0.99

F-HAQ score progression

-0.13 (-2.0 to +1.0)

-0.25 (-2.38 to +0.88)

0.31

-0.13 (-1.88 to +1.00)

-0.38 (-2.38 to +0.88)

0.70

The French version of the Health Assessment Questionnaire (F-HAQ) score was used to quantify functional severity for the whole cohort and for rheumatoid arthritis (RA) patients, whether or not they carried the 196R allele. Values are expressed as median (minimum-maximum).

Goëb et al. Arthritis Research & Therapy 2005 7:R1056   doi:10.1186/ar1777