Table 1 |
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|
Results of immunohistochemistry staining of the synovium of 12 rheumatoid arthritis patients |
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|
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
|
|
|
||||||||||||
|
CD147 |
++ |
++ |
++ |
++ |
+ |
+ |
++ |
+ |
+ |
++ |
+ |
++ |
|
MMP-1 |
++ |
+ |
+ |
++ |
+ |
+ |
++ |
+ |
+ |
++ |
+ |
++ |
|
TIMP-1 |
+ |
+ |
+ |
+ |
- |
+ |
+ |
+ |
+ |
+ |
+ |
- |
|
|
||||||||||||
|
Positive intensity is indicated as: -, positive cell ratio <5%; +, ratio 5% to 50%; ++, ratio >50%. Spearmen's rho analysis showed that expression of CD147 correlated significantly with matrix metalloproteinase-1 (MMP-1) expression (p < 0.05), but that the expression of CD147 and MMP-1 did not correlate with tissue inhibitors of metalloproteinases-1 (TIMP-1) expression (p > 0.05). |
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|
Zhu et al. Arthritis Research & Therapy 2005 7:R1023 doi:10.1186/ar1778 |
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