Table 1

Results of immunohistochemistry staining of the synovium of 12 rheumatoid arthritis patients

1

2

3

4

5

6

7

8

9

10

11

12


CD147

++

++

++

++

+

+

++

+

+

++

+

++

MMP-1

++

+

+

++

+

+

++

+

+

++

+

++

TIMP-1

+

+

+

+

-

+

+

+

+

+

+

-


Positive intensity is indicated as: -, positive cell ratio <5%; +, ratio 5% to 50%; ++, ratio >50%. Spearmen's rho analysis showed that expression of CD147 correlated significantly with matrix metalloproteinase-1 (MMP-1) expression (p < 0.05), but that the expression of CD147 and MMP-1 did not correlate with tissue inhibitors of metalloproteinases-1 (TIMP-1) expression (p > 0.05).

Zhu et al. Arthritis Research & Therapy 2005 7:R1023   doi:10.1186/ar1778

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