Table 1 |
|
|
Classification of neutropenia |
|
| Type of neutropenia |
Neutropenias |
|
|
|
| Congenital |
Severe infantile agranulocytosis (Kostmann's syndrome) |
| Shwachman–Diamond–Oski syndrome |
|
| Myelokathexis/neutropenia with tetraploid nuclei |
|
| Cyclic neutropenia |
|
| Chediak–Higashi syndrome |
|
| Reticular dysgenesis |
|
| Dyskeratosis congenita |
|
| Acquired |
Postinfectious neutropenia |
| Drug-induced neutropenia |
|
| Complement activation (haemodialysis, leukapheresis, ARDS) |
|
| Immune neutropenia |
|
| Isoimmune neonatal neutropenia |
|
| Alloimmune neutropenia (transfusion reaction) |
|
| Autoimmune neutropenia – primary |
|
| Benign of childhood |
|
| Adult chronic form |
|
| Autoimmune neutropenia – secondary |
|
| Autoimmune diseases |
|
| Large granular lymphocyte |
|
| Other (see Table 3) |
|
| Pure white cell aplasia |
|
| Chronic idiopathic neutropenia |
|
| Hypersplenism |
|
| Nutritional deficiency (vitamin B12 or folate deficiency) |
|
| Diseases affecting the bone marrow |
|
| Postchemotherapy |
|
| Aplastic anaemia |
|
| Fanconi anaemia |
|
| Myelodysplastic syndrome |
|
| Acute and chronic leukaemia |
|
|
|
|
|
ARDS, acute respiratory distress syndrome. |
|
|
Capsoni et al. Arthritis Research & Therapy 2005 7:208 doi:10.1186/ar1803 |
|