Table 3 |
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|
Doppler echocardiographic studies in patients with RA |
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|
Reference |
Publication year |
No. of RA patients |
No. of control subjects |
Findings (RA compared to control) |
|
|
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|
Mustonen et al. [86] |
1993 |
12 (males; age 20–40 years) |
14 (males only; unmatched) |
LV diastolic functional impairment No differences in LV systolic function |
|
Corrao et al. [88] |
1996 |
40 |
40 non-RA |
Increased interventricular septal thickness Increased LV mass index LV diastolic functional impairment |
|
Wislowska et al. [89] |
1998 |
100 |
100 non-RA |
Increased LV diastolic diameter Reduced LV ejection fraction |
|
Montecucco et al. [90] |
1999 |
54 |
54 non-RA |
Impaired diastolic relaxation No differences in LV systolic function or LV diastolic diameter |
|
Wislowska et al. [91] |
1999 |
35 with nodular RA |
35 with non-nodular RA |
Increased valvular disease in nodular RA Decreased LV ejection fraction in nodular RA |
|
Di Franco et al. [92] |
2000 |
32 |
33 non-RA (unmatched) |
LV diastolic functional impairment Positive correlation with RA disease duration (r = 0.40) |
|
Cindas et al. [87] |
2002 |
40 |
48 non-RA |
LV diastolic functional impairment Longer disease duration with more abnormal echocardiographic parameters noted |
|
Alpaslan et al. [93] |
2003 |
32 with long standing RA |
32 non-RA (unmatched) |
LV diastolic functional impairment Normal systolic function in all |
|
Levendoglu et al. [94] |
2003 |
40 |
- |
LV diastolic functional impairment Positive correlation with RA disease duration |
|
Gonzalez-Juanatey et al. [55] |
2004 |
47 treated RA patients |
47 |
LV diastolic functional impairment Positive correlation with extra-articular manifestations of RA |
|
|
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|
LV, left ventricular; RA, rheumatoid arthritis. |
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|
Giles et al. Arthritis Research & Therapy 2005 7:195 doi:10.1186/ar1814 |
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