Table 3 |
||||||
|
Nuclear mutational burden data of OA and RA patient tissue and cultured fibroblasts |
||||||
| Patients |
Nucleotides sequenced |
Number of total mutations |
Total mutational burden (mutations/kbp) |
Number of amino acid changes |
Expressed mutational burden (mutations/kbp) |
OA vs RAa |
|
|
||||||
| Fibroblasts |
||||||
| OA |
10971 |
36 |
3.281 |
24 |
2.188 |
|
| RA |
7317 |
15 |
2.050 |
10 |
1.367 |
ρ = 0.2 |
| Tissue |
||||||
| OA |
18287 |
32 |
1.750 |
15 |
0.820 |
|
| RA |
24522 |
41 |
1.672 |
21 |
0.856 |
ρ = 0.2 |
|
|
||||||
|
aTwo-tailed Fisher's exact test. kbp, kilobase pairs; OA, osteoarthritis; RA, rheumatoid arthritis. |
||||||
|
Da Sylva et al. Arthritis Research & Therapy 2005 7:R844 doi:10.1186/ar1752 |
||||||
