Table 1

Characteristics of patients in routine and inception cohorts

Characteristic

Routine cohort (cross-sectional)

Inception cohort (longitudinal)


Patients (n)

767

106

Age (years; mean ± SD)

54.1 ± 14.9

50.5 ± 15.6

Sex (% female)

79.9

75.2

Rheumatoid factor (% positive)

55.3

78.1

Disease duration at baseline (mean ± SD)

8.1 ± 10.6 years

11.5 ± 12.5 weeks

Duration of follow up (years; mean ± SD; range)

-

3.2 ± 1.3; 1–7.25

Disease activity characteristics (median [1st;3rd quartile])

At cross-section

At baseline

Swollen joint count (0–28)

3 (1;7)

7 (4;13)

Tender joint count (0–28)

2 (0;6)

8 (3;16)

ESR (mm; normal <20)

23 (14;55)

49 (24;70)

CRP (mg/dl; normal <1.0)

1.1 (0.5;2.7)

5.1 (1.9;17.0)

Patient assessment of pain (mm; 0–100)

37 (19;53)

50 (32;66)

Patient global assessment of activity (mm; 0–100)

37 (18;58)

51 (33;66)

Evaluator global assessment of activity (mm; 0–100)

34 (19;49)

44 (31;58)

HAQ (0–3)

0.875 (0.25;1.5)

0.75 (0;1.5)

Larsen score

-

1 (0;7)

Completeness of data for analysis

Cross-sectional correlation between composite indices (n [%])

767/767 (100)a

105/106 (99.1%)b

Cross-sectional correlation with HAQ scores (n [%])

720/767 (93.9)

104/106 (98.1)b

Discriminant validity, 1-year follow up (n [%])

-

91/100 (91.0%)

Construct validity, 3-year follow upc (n [%])

-

56/80 (70.0%)


aCompleteness of data was the prerequisite for inclusion. bUsed to validate the results from the cross-sectional analyses in the routine cohort. cIncluding complete radiological data. CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; SD, standard deviation.

Aletaha et al. Arthritis Research & Therapy 2005 7:R796-R806   doi:10.1186/ar1740

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