Table 2

SELDI-TOF MS unpaired serum protein peaks differentially expressed in SJIA before and after conventional therapy

Mass (m/z)
P

4504
0.0004
11650
0.0003
11691
0.0002
14047
0.00001
28107
0.000002
28958
0.0000005
39871
0.0004
46175
0.0008
60806
0.0002

Differences between mass spectra of pretreatment sera of 8 patients who went on to respond to conventional therapy compared with post-treatment sera of 15 patients who responded poorly to conventional therapy. Only variables with nonparametric P values of <0.001 are listed, from 272 peak clusters surveyed. These peaks may represent a profile predictive of response or nonresponse to conventional therapy. SELDI-TOF MS, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry; SJIA, systemic juvenile idiopathic arthritis.

Miyamae et al. Arthritis Research & Therapy 2005 7:R746   doi:10.1186/ar1723

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