Table 5

Partial correlation coefficients between IL-6, rheumatoid factor and glomerular filtration rate, and biomarkers of endothelial dysfunction in rheumatoid arthritis patients

Marker

IL-6

Rheumatoid factor

GFR

R^a

P

R^a

P

R^a

P

VCAM-1 (pg/ml)

0.262

0.04

0.345

0.006

-0.299

0.02

ICAM-1 (pg/ml)

0.263

0.04

0.373

0.003

-0.351

0.005

ELAM-1 (pg/ml)

0.430

0.0005

0.222

0.09

-0.223

0.07

^aThe correlation coefficients shown are controlled for traditional risk factors (age; sex; race; smoking, alcohol and exercising status; diabetes; waist; systolic blood pressure; total cholesterol; high-density lipoprotein cholesterol; triglycerides) in multivariable regression models. ELAM, endothelial leukocyte adhesion molecule; GFR, glomerular filtration rate; ICAM, intercellular adhesion molecule; IL, interleukin; VCAM, vascular adhesion molecule.

Dessein et al. Arthritis Research & Therapy 2005 7:R634   doi:10.1186/ar1717