Table 1

Characteristics of the patients enrolled in the study

Diagnosis

No.

Age

Sex (M/F)

Serum HO-1 (ng/ml)

Serum ferritin (ng/ml)

Hemophagocytic syndrome

7

42.7 (15.5)

1/6

71.2 (72.7)

8485.3 (8388.0)

Adult-onset Still's disease

10

41.0 (11.9)

5/5

102.8 (102.6)

9658.5 (17042.1)

Rheumatic diseases

73

48.2 (15.9)

22/51

3.4 (2.7)

225.5 (709.9)

Rheumatoid arthritis

30

53.1 (13.2)

8/22

2.8 (1.4)

83.0 (95.3)

Systemic lupus erythematosus

18

38.0 (16.8)

1/17

3.2 (1.9)

188.0 (286.3)

Active

12

42.5 (16.4)

1/11

3.6 (2.1)

220.4 (329.8)

Inactive

6

29.0 (15.1)

0/6

2.2 (1.0)

100.6 (122.1)

Behçet's disease

16

47.3 (14.4)

10/6

2.4 (0.8)

48.3 (43.0)

Active

6

46.5 (14.3)

5/1

2.5 (0.5)

61.4 (45.8)

Inactive

10

47.7 (15.3)

5/5

2.3 (1.0)

40.4 (41.7)

Dermatomyositis/polymyositis

9

54.4 (16.6)

3/6

7.4 (5.2)

1097.2 (1827.9)

Liver diseases

20

47.8 (18.1)

16/4

3.7 (2.4)

1032.2 (2496.9)

Acute hepatitis

5

27.8 (5.6)

4/1

4.8 (3.9)

1347.0 (861.0)

Chronic hepatitis

7

51.9 (12.5)

6/1

3.8 (1.6)

159.9 (128.0)

Liver cirrhosis

2

69.0 (7.1)

2/0

5.8 (1.4)

102.0 (28.3)

Hepatocellular carcinoma

2

59.5 (10.6)

2/0

1.9 (0.7)

260.0 (134.4)

Primary biliary cirrhosis

2

46.0 (21.2)

1/1

2.8 (3.0)

373.5 (892.4)

Autoimmune hepatitis

1

34

0/1

2.9

11262

Alcoholic hepatitis

1

71

1/0

2.8

56

Hematological diseases

10

62.3 (15.3)

6/4

4.3 (2.4)

2822.6 (2817.3)

Myelodysplastic syndrome

6

59.3 (22.5)

4/2

3.7 (2.6)

1883.8 (1885.9)

Aplastic anemia

4

54.0 (18.8)

2/2

5.1 (2.1)

4230.8 (3671.1)

Healthy controls

22

30.8 (7.6)

16/6

2.6 (1.3)

93.0 (56.9)

Data are shown as means (standard deviations). F, female; HO, heme oxygenase; M, male.

Kirino et al. Arthritis Research & Therapy 2005 7:R616   doi:10.1186/ar1721