Histology of pellets. The figure shows stained sections of pellets from the unaffected and affected side from same OA donors ((a–f) female, age 81 years and (g–l) male, age 74 years) as shown in Fig. 1. (a, d, g, f) Alcian blue–van Gieson staining indicating the accumulation of proteoglycans. (b, e, h, k) Immunohistochemical staining with anti-type II collagen antibody. (c, f, i, l) Immunohistochemical staining with anti-type I collagen antibody. Positive staining is indicated by a red colour in the extracellular matrix.
Tallheden et al. Arthritis Research & Therapy 2005 7:R560 doi:10.1186/ar1709