Histology of biopsies. The figure shows sections stained with Alcian blue/van Gieson. The biopsies originate from two representative autologous chondrocyte transplantation patients (ACT) (a, b) and from the unaffected and affected side from two patients with osteoarthritis (OA) undergoing total knee replacement (c–f). (c, e) Biopsy from one OA donor (female, aged 81 years) with a Mankin score of 1.5 on both sides. (d, f) Biopsy from another OA donor (male, aged 74 years) with Mankin scores of 5 (d) and 11 (f).
Tallheden et al. Arthritis Research & Therapy 2005 7:R560-R568 doi:10.1186/ar1709