Table 5

FBAT-e analyses using setafftrait 1 0 0, testing specifically for affected men

Marker

Allele

Allele frequency

Number of informative families

Z score

P


Additive model: biallelic test


D5S1953

2

0.44

47

0.25

0.805

rs26307

C

0.80

22

2.06

0.039*

rs27356

C

0.79

25

2.63

0.008*

3088132

G

0.79

18

1.23

0.216

rs153929

A

0.76

36

0.49

0.619

rs258215

A

0.58

32

0.81

0.419

rs28006

T

0.26

37

0.15

0.877

rs25957

C

0.77

33

0.76

0.446

ANKH-OR

1

0.48

64

1.04

0.297

D5S1991

2

0.49

64

0.39

0.696

D5S1954

2

0.36

49

0.33

0.736


Recessive model: biallelic test


D5S1953

1

0.56

40

-0.83

0.406

rs26307

C

0.81

25

2.51

0.012*

rs27356

C

0.80

28

2.99

0.002*

3088132

G

0.79

22

1.44

0.149

rs153929

A

0.76

39

0.71

0.477

rs258215

A

0.59

23

0.60

0.543

rs28006

T

0.26

16

0.33

0.739

rs25957

C

0.76

29

0.64

0.518

ANKH-OR

2

0.52

44

-1.26

0.205

D5S1991

1

0.51

46

-0.71

0.472

D5S1954

1

0.64

43

-0.65

0.510


*Statistically significant findings. FBAT, family-based association testing.

Tsui et al. Arthritis Research & Therapy 2005 7:R513-R525   doi:10.1186/ar1701

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