Table 4 |
|||||
|
FBAT-e analyses using setafftrait 0 -1 0, testing specifically for affected women |
|||||
|
Marker |
Allele |
Allele frequency |
Number of informative families |
Z score |
P |
|
|
|||||
|
Additive model: biallelic test |
|||||
|
|
|||||
|
D5S1953 |
1 |
0.56 |
47 |
0.47 |
0.635 |
|
rs26307 |
T |
0.19 |
22 |
0.32 |
0.751 |
|
rs27356 |
T |
0.20 |
24 |
1.03 |
0.302 |
|
3088132 |
C |
0.21 |
20 |
0.37 |
0.712 |
|
rs153929 |
G |
0.24 |
46 |
1.31 |
0.191 |
|
rs258215 |
T |
0.41 |
30 |
1.54 |
0.123 |
|
rs28006 |
T |
0.26 |
31 |
2.82 |
0.004* |
|
rs25957 |
G |
0.23 |
23 |
2.82 |
0.004* |
|
ANKH-OR |
2 |
0.52 |
59 |
0.94 |
0.347 |
|
D5S1991 |
1 |
0.52 |
53 |
1.10 |
0.270 |
|
D5S1954 |
2 |
0.36 |
45 |
1.38 |
0.168 |
|
|
|||||
|
Recessive model: biallelic test |
|||||
|
|
|||||
|
D5S1953 |
2 |
0.44 |
39 |
-1.21 |
0.227 |
|
rs26307 |
C |
0.81 |
26 |
0.52 |
0.606 |
|
rs27356 |
T |
0.20 |
10 |
1.81 |
0.069 |
|
3088132 |
G |
0.79 |
22 |
0.08 |
0.930 |
|
rs153929 |
A |
0.76 |
44 |
-1.39 |
0.162 |
|
rs258215 |
A |
0.58 |
21 |
-1.76 |
0.077 |
|
rs28006 |
C |
0.74 |
28 |
-2.49 |
0.012* |
|
rs25957 |
C |
0.76 |
23 |
-2.25 |
0.024* |
|
ANKH-OR |
2 |
0.52 |
34 |
1.14 |
0.254 |
|
D5S1991 |
1 |
0.51 |
33 |
1.52 |
0.127 |
|
D5S1954 |
1 |
0.64 |
45 |
-1.54 |
0.122 |
|
|
|||||
|
*Statistically significant findings. FBAT, family-based association testing. |
|||||
|
Tsui et al. Arthritis Research & Therapy 2005 7:R513 doi:10.1186/ar1701 |
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