Table 4

FBAT-e analyses using setafftrait 0 -1 0, testing specifically for affected women

Marker

Allele

Allele frequency

Number of informative families

Z score

P


Additive model: biallelic test


D5S1953

1

0.56

47

0.47

0.635

rs26307

T

0.19

22

0.32

0.751

rs27356

T

0.20

24

1.03

0.302

3088132

C

0.21

20

0.37

0.712

rs153929

G

0.24

46

1.31

0.191

rs258215

T

0.41

30

1.54

0.123

rs28006

T

0.26

31

2.82

0.004*

rs25957

G

0.23

23

2.82

0.004*

ANKH-OR

2

0.52

59

0.94

0.347

D5S1991

1

0.52

53

1.10

0.270

D5S1954

2

0.36

45

1.38

0.168


Recessive model: biallelic test


D5S1953

2

0.44

39

-1.21

0.227

rs26307

C

0.81

26

0.52

0.606

rs27356

T

0.20

10

1.81

0.069

3088132

G

0.79

22

0.08

0.930

rs153929

A

0.76

44

-1.39

0.162

rs258215

A

0.58

21

-1.76

0.077

rs28006

C

0.74

28

-2.49

0.012*

rs25957

C

0.76

23

-2.25

0.024*

ANKH-OR

2

0.52

34

1.14

0.254

D5S1991

1

0.51

33

1.52

0.127

D5S1954

1

0.64

45

-1.54

0.122


*Statistically significant findings. FBAT, family-based association testing.

Tsui et al. Arthritis Research & Therapy 2005 7:R513-R525   doi:10.1186/ar1701

Open Data