Arthritis Research & Therapy

official impact factor 4.36

Open Access Highly Access

Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

David A Young, Rachel L Lakey, Caroline J Pennington, Debra Jones, Lara Kevorkian, Dylan R Edwards, Timothy E Cawston and Ian M Clark*

Arthritis Research & Therapy 2005, 7:R503-R512 doi:10.1186/ar1702

Accesses  

  • Last 30 days: 61 accesses
  • Last year: 775 accesses
  • All time: 7090 accesses

Cited by

BioMed Central: 4 citations

Research article   Open Access

Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism

Sridar V Chittur, Niquiche Sangster-Guity, Paulette J McCormick BMC Genomics 2008, 9:507 (29 October 2008)

Review   Free

Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

Aleksander M Grabiec, Paul P Tak, Kris A Reedquist Arthritis Research & Therapy 2008, 10:226 (17 October 2008)

Research article   Open Access Highly Accessed

Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis

Jennifer M Milner, Andrew D Rowan, Tim E Cawston, David A Young Arthritis Research & Therapy 2006, 8:R142 (18 August 2006)

Commentary   Free

Histone deacetylases – a new target for suppression of cartilage degradation?

John S Mort Arthritis Research & Therapy 2005, 7:155-156 (16 June 2005)