Table 2

Correlation between mRNA expression and severity of knee joint swelling in rats with AIA

Cytokine

Day(s)

Correlationa

Pa

ρa

n


Synovial membrane


IL-1β

0–6

+

0.05

0.527

25

IL-6

0–6

+

0.03

0.405

28


Inguinal lymph node


IL-6

3

+

0.02

0.886

6


Spleen


IL-6

0–6

+

0.01

0.511

25

IL-5

6

-

<0.001

1.000

4

IL-10

6

-

0.04

0.829

6


aSpearman rank correlation. +, positive; -, negative; AIA, antigen-induced arthritis.

Pohlers et al. Arthritis Research & Therapy 2005 7:R445-R457   doi:10.1186/ar1689

Open Data