Table 3

Factor analysis on cytokines and neuropeptides in synovial fluid

Variable

Factor


1

2

3

4


TNF-α

0.751

IL-6

0.913

MCP-1

0.912

BN/GRP

-0.436

0.623

0.327

SP

0.409

0.33

0.361

0.671

VIP

0.784

CGRP

0.715

-0.472

NPY

0.893

ESR

0.71


Principal-component analysis for cytokines and neuropeptides in synovial fluid from 23 patients with long-standing RA, and for the ESR. BN/GRP, bombesin/gastrin-releasing peptide; CGRP, calcitonin-gene-related peptide; ESR, erythrocyte sedimentation rate; MCP, monocyte chemoattractant protein-1; NPY, neuropeptide Y; RA, rheumatoid arthritis; SP, substance P; TNF, tumour necrosis factor; VIP, vasoactive intestinal peptide.

Grimsholm et al. Arthritis Research & Therapy 2005 7:R416-R426   doi:10.1186/ar1503

Open Data