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Volume 7 Issue 3

Comment

Viewpoint   Free

Cold hands – strained heart? Advances in the management of Raynaud's phenomenon and pulmonary hypertension

Frances C Hall Arthritis Research & Therapy 2005, 7:126-128 (18 April 2005)

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Commentary   Free

Gastrin-releasing peptide, substance P and cytokines in rheumatoid arthritis

Paul G Green Arthritis Research & Therapy 2005, 7:111-113 (30 March 2005)

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Commentary   Free

Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E2

Annaleise V Sampey, Seetha Monrad, Leslie J Crofford Arthritis Research & Therapy 2005, 7:114-117 (6 April 2005)

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Commentary   Free

Role of regulatory T cells in experimental arthritis and implications for clinical use

Marco Londei Arthritis Research & Therapy 2005, 7:118-120 (7 April 2005)

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Commentary   Free

Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification?

Filip Van den Bosch, Filip De Keyser, Herman Mielants, Eric M Veys Arthritis Research & Therapy 2005, 7:121-123 (11 April 2005)

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Commentary   Free

Psoriatic arthritis synovial histopathology: commentary on the article by Kruithof and colleagues

Oliver FitzGerald Arthritis Research & Therapy 2005, 7:124-125 (18 April 2005)

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Review

Review   Free

Regulatory T cells in rheumatoid arthritis

Jan Leipe, Alla Skapenko, Peter E Lipsky, Hendrik Schulze-Koops Arthritis Research & Therapy 2005, 7:93-99 (9 March 2005)

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Negative regulation of cytokine signaling and immune responses by SOCS proteins

Akihiko Yoshimura, Hitomi Nishinakamura, Yumiko Matsumura, Toshikatsu Hanada Arthritis Research & Therapy 2005, 7:100-110 (30 March 2005)

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Report

Correction   Free

Correction: Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab

Xenofon Baraliakos, Joachim Listing, Jan Brandt, Angela Zink, Rieke Alten, Gerd Burmester, Erika Gromnica-Ihle, Herbert Kellner, Matthias Schneider, Helmut Sörensen, Hennig Zeidler, Martin Rudwaleit, Joachim Sieper, Juergen Braun Arthritis Research & Therapy 2005, 7:113 (23 March 2005)

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Research

Research article   Open Access

Levels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis

Ola Grimsholm, Solbritt Rantapää-Dahlqvist, Sture Forsgren Arthritis Research & Therapy 2005, 7:R416-R426 (7 February 2005)

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Research article   Open Access

Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis

Dirk Pohlers, Angela Siegling, Eberhard Buchner, Carsten B Schmidt-Weber, Ernesta Palombo-Kinne, Frank Emmrich, Rolf Bräuer, Raimund W Kinne Arthritis Research & Therapy 2005, 7:R445-R457 (17 February 2005)

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Research article   Open Access

Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts

Shingo Nakayamada, Hitoshi Kurose, Kazuyoshi Saito, Akira Mogami, Yoshiya Tanaka Arthritis Research & Therapy 2005, 7:R476-R484 (18 February 2005)

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A web tool for finding gene candidates associated with experimentally induced arthritis in the rat

Lars Andersson, Greta Petersen, Per Johnson, Fredrik Ståhl Arthritis Research & Therapy 2005, 7:R485-R492 (18 February 2005)

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Research article   Open Access

Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis

Loes Linsen, Marielle Thewissen, Kurt Baeten, Veerle Somers, Piet Geusens, Jef Raus, Piet Stinissen Arthritis Research & Therapy 2005, 7:R493-R502 (18 February 2005)

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The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-κB transcriptional activity in models of rheumatoid arthritis

James C Keith, Leo M Albert, Yelena Leathurby, Max Follettie, Lili Wang, Lisa Borges-Marcucci, Christopher C Chadwick, Robert J Steffan, Douglas C Harnish Arthritis Research & Therapy 2005, 7:R427-R438 (21 February 2005)

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Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab

Xenofon Baraliakos, Joachim Listing, Jan Brandt, Martin Rudwaleit, Joachim Sieper, Juergen Braun Arthritis Research & Therapy 2005, 7:R439-R444 (21 February 2005)

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Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity

Karin Lundberg, Suzanne Nijenhuis, Erik R Vossenaar, Karin Palmblad, Walter J van Venrooij, Lars Klareskog, AJW Zendman, Helena Harris Arthritis Research & Therapy 2005, 7:R458-R467 (21 February 2005)

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Research article   Open Access

The P2X7 receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products

James I Elliott, John H McVey, Christopher F Higgins Arthritis Research & Therapy 2005, 7:R468-R475 (21 February 2005)

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Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

David A Young, Rachel L Lakey, Caroline J Pennington, Debra Jones, Lara Kevorkian, Dylan R Edwards, Timothy E Cawston, Ian M Clark Arthritis Research & Therapy 2005, 7:R503-R512 (22 February 2005)

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ANKH variants associated with ankylosing spondylitis: gender differences

Hing Tsui, Robert D Inman, Andrew D Paterson, John D Reveille, Florence WL Tsui Arthritis Research & Therapy 2005, 7:R513-R525 (25 February 2005)

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Research article   Open Access

The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death

Hyun A Kim, Ki Byoung Lee, Sang-cheol Bae Arthritis Research & Therapy 2005, 7:R526-R535 (1 March 2005)

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Research article   Open Access

Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes

René J Berckmans, Rienk Nieuwland, Maarten C Kraan, Marianne CL Schaap, Desirée Pots, Tom JM Smeets, Augueste Sturk, Paul P Tak Arthritis Research & Therapy 2005, 7:R536-R544 (1 March 2005)

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Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey

Michel De Bandt, Jean Sibilia, Xavier Le Loët, Sebastian Prouzeau, Bruno Fautrel, Christian Marcelli, Eric Boucquillard, Jean Siame, Xavier Mariette, the Club Rhumatismes et Inflammation Arthritis Research & Therapy 2005, 7:R545-R551 (1 March 2005)

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Quantitative ultrasound can assess the regeneration process of tissue-engineered cartilage using a complex between adherent bone marrow cells and a three-dimensional scaffold

Koji Hattori, Yoshinori Takakura, Hajime Ohgushi, Takashi Habata, Kota Uematsu, Jun Yamauchi, Kenji Yamashita, Takashi Fukuchi, Masao Sato, Ken Ikeuchi Arthritis Research & Therapy 2005, 7:R552-R559 (1 March 2005)

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Proliferation and differentiation potential of chondrocytes from osteoarthritic patients

Tommi Tallheden, Catherine Bengtsson, Camilla Brantsing, Eva Sjögren-Jansson, Lars Carlsson, Lars Peterson, Mats Brittberg, Anders Lindahl Arthritis Research & Therapy 2005, 7:R560-R568 (3 March 2005)

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Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis

Elli Kruithof, Dominique Baeten, Leen De Rycke, Bernard Vandooren, Dirk Foell, Johannes Roth, Juan D Cañete, Annemieke M Boots, Eric M Veys, Filip De Keyser Arthritis Research & Therapy 2005, 7:R569-R580 (3 March 2005)

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Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

Miguel Otero, Rocío Lago, Francisca Lago, Juan Reino, Oreste Gualillo Arthritis Research & Therapy 2005, 7:R581-R591 (4 March 2005)

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Research article   Open Access

Anti-Sa antibodies and antibodies against cyclic citrullinated peptide are not equivalent as predictors of severe outcomes in patients with recent-onset polyarthritis

Gilles Boire, Pierre Cossette, Artur J de Brum-Fernandes, Patrick Liang, Théophile Niyonsenga, Zhijie J Zhou, Nathalie Carrier, Claude Daniel, Henri-A Ménard Arthritis Research & Therapy 2005, 7:R592-R603 (17 March 2005)

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Research article   Open Access

CD134 as target for specific drug delivery to auto-aggressive CD4+ T cells in adjuvant arthritis

Elmieke PJ Boot, Gerben A Koning, Gert Storm, Josée PA Wagenaar-Hilbers, Willem van Eden, Linda A Everse, Marca HM Wauben Arthritis Research & Therapy 2005, 7:R604-R615 (21 March 2005)

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Increased serum HO-1 in hemophagocytic syndrome and adult-onset Still's disease: use in the differential diagnosis of hyperferritinemia

Yohei Kirino, Mitsuhiro Takeno, Mika Iwasaki, Atsuhisa Ueda, Shigeru Ohno, Akira Shirai, Heiwa Kanamori, Katsuaki Tanaka, Yoshiaki Ishigatsubo Arthritis Research & Therapy 2005, 7:R616-R624 (21 March 2005)

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Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]

Tim D Spector, Philip G Conaghan, J Christopher Buckland-Wright, Patrick Garnero, Gary A Cline, John F Beary, David J Valent, Joan M Meyer Arthritis Research & Therapy 2005, 7:R625-R633 (24 March 2005)

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Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis

Patrick H Dessein, Barry I Joffe, Sham Singh Arthritis Research & Therapy 2005, 7:R634-R643 (24 March 2005)

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Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports

R Andrew Moore, Sheena Derry, Geoffrey T Makinson, Henry J McQuay Arthritis Research & Therapy 2005, 7:R644-R665 (24 March 2005)

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Intra-articular injections of high-molecular-weight hyaluronic acid have biphasic effects on joint inflammation and destruction in rat antigen-induced arthritis

Andreas Roth, Jürgen Mollenhauer, Andreas Wagner, Reneè Fuhrmann, Albrecht Straub, Rudolf A Venbrocks, Peter Petrow, Rolf Bräuer, Harald Schubert, Jörg Ozegowski, Gundela Peschel, Peter J Müller, Raimund W Kinne Arthritis Research & Therapy 2005, 7:R677-R686 (31 March 2005)

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Research article   Open Access

The determinants of change in tibial plateau bone area in osteoarthritic knees: a cohort study

Yuanyuan Wang, Anita E Wluka, Flavia M Cicuttini Arthritis Research & Therapy 2005, 7:R687-R693 (31 March 2005)

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Research article   Open Access

The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function

Bernhard M Kirsch, Maximilian Zeyda, Karl Stuhlmeier, Johannes Grisar, Josef S Smolen, Bruno Watschinger, Thomas M Stulnig, Walter H Hörl, Gerhard J Zlabinger, Marcus D Säemann Arthritis Research & Therapy 2005, 7:R694-R703 (1 April 2005)

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Clinical evaluation of autoantibodies to a novel PM/Scl peptide antigen

Michael Mahler, Reinout Raijmakers, Cornelia Dähnrich, Martin Blüthner, Marvin J Fritzler Arthritis Research & Therapy 2005, 7:R704-R713 (1 April 2005)

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Dermatological conditions during TNF-α-blocking therapy in patients with rheumatoid arthritis: a prospective study

Marcel Flendrie, Wynand HPM Vissers, Marjonne CW Creemers, Elke MGJ de Jong, Peter CM van de Kerkhof, Piet LCM van Riel Arthritis Research & Therapy 2005, 7:R666-R676 (4 April 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

TNF-α blocking therapies have shown considerable success in moderating disease activity in rheumatic diseases, however a recent study has shown that in 25% of patients, their prescription results in dermatological conditions, including eczema and skin infections.


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