|
Characteristics of the study population |
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| Traditional nonselective NSAIDs (n = 12,418) |
Celecoxib (n = 42,422) |
Rofecoxib (n = 25,674) |
|
|
|
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| Age (years) |
|||
| 18–34 |
18.6 |
3.7 |
6.7 |
| 35–44 |
15.8 |
6.5 |
9.7 |
| 45–54 |
13.2 |
9.9 |
12.1 |
| 55–64 |
13.5 |
15.9 |
16.4 |
| 65–74 |
18.8 |
30.5 |
27.1 |
| 75–84 |
15.1 |
27.1 |
22.7 |
| 85+ |
4.1 |
6.5 |
5.1 |
| Sex |
|||
| Female |
55.4 |
67.4 |
65.5 |
| Male |
44.6 |
32.6 |
34.5 |
| Income level |
|||
| Low |
14.8 |
10.9 |
11.4 |
| Nonlow |
85.2 |
89.1 |
88.6 |
| Dosage category |
|||
| High |
11.6 |
31.2 |
8.8 |
| Standard |
66.3 |
65.3 |
73.0 |
| Low |
22.1 |
3.4 |
18.2 |
| Prior diagnosis of gastropathy |
3.6 |
7.7 |
5.0 |
| Prior gastrointestinal procedures |
2.0 |
4.5 |
2.7 |
| Prior dispensation of gastroprotective agents |
14.0 |
29.9 |
24.3 |
| Prior referral to a gastroenterologist |
2.8 |
6.0 |
3.9 |
| History of NSAID use |
|||
| Recent, first time |
3.0 |
2.2 |
2.8 |
| Recent, chronic |
6.6 |
4.3 |
4.2 |
| >1 to 3 months |
15.7 |
7.8 |
6.3 |
| >3 to 12 months |
19.4 |
22.0 |
14.0 |
| No use |
55.2 |
63.7 |
72.8 |
| Anticoagulants |
1.3 |
3.3 |
3.0 |
| Corticosteroids |
11.7 |
19.6 |
16.9 |
| Benzodiazepines |
23.3 |
38.2 |
33.0 |
| Antidepressants |
10.5 |
17.2 |
15.7 |
| Chronic Disease Score |
|||
| ≥10 |
5.2 |
10.3 |
8.2 |
| 5–9 |
19.6 |
28.6 |
25.4 |
| 1–4 |
27.9 |
33.6 |
32.6 |
| 0 |
47.3 |
27.6 |
33.8 |
| Prescriber specialty |
|||
| General practitioner |
85.9 |
85.3 |
88.3 |
| Cardiology |
1.0 |
0.4 |
0.3 |
| Internal Medicine |
2.3 |
3.3 |
2.1 |
| Neurology |
0.3 |
0.3 |
0.2 |
| General surgery |
1.4 |
0.8 |
1.0 |
| Obstetrics/gynaecology |
1.5 |
0.2 |
0.3 |
| Orthopaedic surgery |
1.2 |
3.4 |
3.2 |
| Rheumatology |
2.5 |
2.5 |
1.7 |
| Other |
2.8 |
3.8 |
2.9 |
|
Values are expressed as percentages. NSAID, nonsteroidal anti-inflammatory drug. | |||
Moride et al. Arthritis Res Ther 2005 7:R333 doi:10.1186/ar1488 |
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