Table 2 |
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|
Transmission disequilibrium test analysis of the US and UK systemic onset juvenile rheumatoid arthritis families using Transmit |
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|
Arg260 transmission |
Thr260 transmission |
||||||
|
|
|||||||
|
SoJRA families |
n |
Observed |
Expected |
Observed |
Expected |
χ2 (1 df) |
P |
|
|
|||||||
|
US only |
82 |
99 |
(88.0) |
65 |
(75.9) |
6.0* |
0.01* |
|
US unaffected siblings |
79 |
82 |
(77.5) |
76 |
(80.5) |
1.04 |
0.3 |
|
UK only |
74 |
91 |
(89.0) |
57 |
(58.0) |
0.08 |
0.78 |
|
UK and US together |
156 |
190 |
(177.8) |
122 |
(134.2) |
4.2* |
0.04* |
|
|
|||||||
|
*Significant findings. n, number of informative families for transmission; UK, British Paediatric Rheumatology Study Group cohort; US, Cincinnati cohort. |
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|
Bukulmez et al. Arthritis Res Ther 2005 7:R285 doi:10.1186/ar1480 |
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