Table 1

Tapasin genotypic distributions in systemic onset juvenile rheumatoid arthritis families

Tapasin genotypes

US healthy control individuals

US healthy siblings of SoJRA

US SoJRA

UK SoJRA

UK and US SoJRA


0101

35 (31.0%)

26 (28.0%)

49 (36.6%)

23 (30.0%)

72 (34.4%)

0102

56 (49.5%)

50 (53.7%)

63 (47.0%)

45 (60.0%)

108 (51.6%)

0202

22 (19.5%)

17 (18.3%)

22 (16.4%)

7 (9.2%)

29 (14.0%)

01 allele frequency

0.56

0.55

0.6

0.6

0.6

02 allele frequency

0.44

0.45

0.4

0.4

0.4

Total

113

93

134

76

209


Tapasin 01 allele is Arg260, and 02 is Thr260. SoJRA, systemic onset juvenile rheumatoid arthritis.

Bukulmez et al. Arthritis Res Ther 2005 7:R285-R290   doi:10.1186/ar1480

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