Figure 1.

Effect of hyaluronic acid (HA) on antithrombin (AT). Various concentrations of HA, digested or not with hyaluronidase, were incubated with antithrombin in the presence of 5 mmol/l CaCl₂ or FeCl₃. Thrombin activity in the absence of both HA and antithrombin (blank) was considered as 1 and the activities of the other tests were normalized based on comparisons with blank. Values are expressed as mean ± standard deviation of data from triplicate experiments.