|
Experimental groups used for adoptive disease transfer and differential expression analysis |
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| Group |
RNA source |
Treatment |
Days after injection |
No. of animals |
|
|
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| AN |
Naive control (absolute negative) BALB/cSCID paw |
None |
N/A |
3 |
| PA |
Normal paw from arthritic BALB/cSCID mouse |
Cell transfer |
6 |
3 |
| AA |
Acute arthritic paw of BALB/cSCID mouse |
Cell transfer |
6 |
5 |
| CA |
Chronically arthritic paw of BALB/cSCID mouse |
Cell transfer |
12–14 |
3 |
|
Group AN represents naive BALB/cSCID mice that received no cells. Experimental groups PA, AA, and CA received antigen-stimulated lymphocytes from arthritic BALB/c donor mice. RNA was isolated from four paws of two mice at the indicated number of days after injection, and pooled. | ||||
Adarichev et al. Arthritis Res Ther 2005 7:R196 doi:10.1186/ar1472 |
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