Table 2

Characteristics of human herpesviruses, Chlamydiae and parvovirus

Organism
Receptors
Main cellular tropism
Proposed latency cell
Other tropism
References

EBV
CD21, MHC-II, α5β1 integrin
B
B
EPC, EC
[8]
CMV
EGFR
M/M
M/M; EC
N, EPC, EC
[174]
HHV6
CD46+
M/M, T, B
M/M
N, EPC
[175]
HHV7
CD4+ heparan sulfate receptor
T
M/M
N, EPC, EC
[176,177]
HHV8
Heparan sulfate receptor, EGFR
EC, M/M, B, T
B
N, EPC
[174,178]
Chlamydia pneumoniae
Heparan sulfate receptor
M/M

EC, EPC
[179]
Chlamydia trachomatis

M/M

EC, EPC

Parvovirus B19
Erythrocyte P antigen
Erythroid precursors

EC
[66,67]

B, B cells; CMV, cytomegalovirus; EBV, Epstein–Barr virus; EC, endothelial cells; EGFR, epidermal growth factor receptor; EPC, epithelial cells; HHV, human herpesvirus; MHC, major histocompatibility complex; M/M, myelomonocytic cells; N, neural cells; T, T cells.

Posnett and Yarilin Arthritis Research & Therapy 2005 7:74   doi:10.1186/ar1691