|
Down-regulated genes in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLSs) stimulated with protein I/II. Confluent RA FLSs were stimulated with protein I/II for 4 hours or left untreated as controls. Total RNA was isolated, reverse-transcribed into 32P-labeled cDNA, and hybridized to Atlas human cancer cDNA expression arrays. The values are expression ratios (protein I/II / control). |
||||
| RA patient |
||||
|
|
||||
| Protein product of gene |
GenBank accession no. |
1 |
2 |
3 |
|
|
||||
| Insulin-like growth factor binding protein-4 |
M62403 |
0.1 |
0.2 |
0.2 |
| Insulin-like growth factor binding protein-5 |
M65062 |
- |
0.2 |
- |
| Cyclin-dependent kinase 4 inhibitor D |
U40343 |
- |
- |
0.3 |
| Ubiquitin-conjugating enzyme E2A |
M74524 |
- |
- |
0.3 |
| Methallothionein III |
D13365 |
0.3 |
- |
- |
Zeisel et al. Arthritis Res Ther 2005 7:R118 doi:10.1186/ar1462 |
||||