Arthritis Research & Therapy

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Open Access Research article

Gene expression profiles in the rat streptococcal cell wall-induced arthritis model identified using microarray analysis

Inmaculada Rioja1*, Chris L Clayton2, Simon J Graham2, Paul F Life1 and Marion C Dickson1

Author Affiliations

1 Rheumatoid Arthritis Disease Biology Department, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK

2 Transcriptome Analysis Department, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK

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Arthritis Res Ther 2005, 7:R101-R117 doi:10.1186/ar1458

Published: 19 November 2004

Additional files

Additional File 1:

Excel spreadsheets summarizing all of the genes upregulated (Delta > 1.8 and P < 0.01) and downregulated (Delta < 1.8 and P < 0.01) in ankle joints from SCW-induced arthritis in Lewis (LEW/N) rats on days -13.8 (4 hours after intra-articular injection of SCW), -13 and 3. Data are expressed as the mean fold increase in gene expression (D = Delta) in SCW-injected animals compared with the expression in the corresponding PBS control group, along with P values.

Format: XLS Size: 143KB Download file

This file can be viewed with: Microsoft Excel Viewer

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