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Volume 7 Issue 1

Comment

Viewpoint   Free

Direct interaction of immunoglobulins with synovial fibroblasts: a missing link in the pathogenesis of rheumatoid arthritis?

Thomas Pap Arthritis Res Ther 2005, 7:44-46 (20 December 2004)

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Commentary   Free

Interleukin-18: a therapeutic target in rheumatoid arthritis?

Iain B McInnes, Foo Y Liew, J Alastair Gracie Arthritis Res Ther 2005, 7:38-41 (17 December 2004)

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Commentary   Free

Interleukin-7 deficiency in rheumatoid arthritis

Warren J Leonard Arthritis Res Ther 2005, 7:42-43 (20 December 2004)

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Review

Review   Free

Mast cells in inflammatory arthritis

Peter A Nigrovic, David M Lee Arthritis Res Ther 2005, 7:1-11 (2 November 2004)

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Review   Free Highly Accessed

Toll-like receptor downstream signaling

Taro Kawai, Shizuo Akira Arthritis Res Ther 2005, 7:12-19 (30 November 2004)

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Review   Free

The role and clinical implications of G6PI in experimental models of rheumatoid arthritis

Thomas Kamradt, David Schubert Arthritis Res Ther 2005, 7:20-28 (30 November 2004)

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Review   Free

The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models

Erik Lubberts, Marije I Koenders, Wim B van den Berg Arthritis Res Ther 2005, 7:29-37 (30 November 2004)

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Research

Research article   Open Access

Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants

Tabassum Naqvi, Trang T Duong, Gihan Hashem, Momotoshi Shiga, Qin Zhang, Sunil Kapila Arthritis Res Ther 2005, 7:R1-R11 (29 October 2004)

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Research article   Open Access

p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis

Yuji Yamanishi, David L Boyle, Douglas R Green, Edward C Keystone, Alison Connor, Susan Zollman, Gary S Firestein Arthritis Res Ther 2005, 7:R12-R18 (29 October 2004)

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Research article   Open Access

Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies

Michael Mahler, Marvin J Fritzler, Martin Blüthner Arthritis Res Ther 2005, 7:R19-R29 (10 November 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Anti-SMP antibodies are exclusively present in sera of systemic lupus erythrematosus (SLE) patients; this new serological marker has been used to develop an anti-SMP ELISA test, improving diagnosis of SLE.

Research article   Open Access

Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome

Joyce Villanueva, Susan Lee, Edward H Giannini, Thomas B Graham, Murray H Passo, Alexandra Filipovich, Alexei A Grom Arthritis Res Ther 2005, 7:R30-R37 (10 November 2004)

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Research article   Open Access

A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL

Wang Hui, Tim E Cawston, Carl D Richards, Andrew D Rowan Arthritis Res Ther 2005, 7:R57-R64 (10 November 2004)

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Research article   Open Access

Serum cathepsin K levels of patients with longstanding rheumatoid arthritis: correlation with radiological destruction

Martin Skoumal, Günther Haberhauer, Gernot Kolarz, Gerhard Hawa, Wolfgang Woloszczuk, Anton Klingler Arthritis Res Ther 2005, 7:R65-R70 (10 November 2004)

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Research article   Open Access

Elevated matrix metalloproteinase-9 in patients with systemic sclerosis

Wan-Uk Kim, So-Youn Min, Mi-La Cho, Kyung-Hee Hong, Yong-Joo Shin, Sung-Hwan Park, Chul-Soo Cho Arthritis Res Ther 2005, 7:R71-R79 (10 November 2004)

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Research article   Open Access

Quantitative ultrasonic assessment for detecting microscopic cartilage damage in osteoarthritis

Koji Hattori, Ken Ikeuchi, Yusuke Morita, Yoshinori Takakura Arthritis Res Ther 2005, 7:R38-R46 (16 November 2004)

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Research article   Open Access

The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin

Ian Giles, Nancy Lambrianides, David Latchman, Pojen Chen, Reginald Chukwuocha, David Isenberg, Anisur Rahman Arthritis Res Ther 2005, 7:R47-R56 (16 November 2004)

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Research article   Open Access Highly Accessed

Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia

Frederique Ponchel, Robert J Verburg, Sarah J Bingham, Andrew K Brown, John Moore, Andrew Protheroe, Kath Short, Catherine A Lawson, Ann W Morgan, Mark Quinn, Maya Buch, Sarah L Field, Sarah L Maltby, Aurelie Masurel, Susan H Douglas, Liz Straszynski, Ursula Fearon, Douglas J Veale, Poulam Patel, Dennis McGonagle, John Snowden, Alexander F Markham, David Ma, Jacob M van Laar, Helen A Papadaki, Paul Emery, John D Isaacs Arthritis Res Ther 2005, 7:R80-R92 (16 November 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Lower levels of the cytokine IL-7 in rheumatoid arthritis patients contribute to diminished T-cell reconstitution following lymphodepleting therapy.

Research article   Open Access

Nifedipine protects against overproduction of superoxide anion by monocytes from patients with systemic sclerosis

Yannick Allanore, Didier Borderie, Axel Périanin, Hervé Lemaréchal, Ohvanesse Ekindjian, André Kahan Arthritis Res Ther 2005, 7:R93-R100 (16 November 2004)

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Research article   Open Access

Gene expression profiles in the rat streptococcal cell wall-induced arthritis model identified using microarray analysis

Inmaculada Rioja, Chris L Clayton, Simon J Graham, Paul F Life, Marion C Dickson Arthritis Res Ther 2005, 7:R101-R117 (19 November 2004)

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Research article   Open Access

MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β1

Mirjam B Zeisel, Vanessa A Druet, Dominique Wachsmann, Jean Sibilia Arthritis Res Ther 2005, 7:R118-R126 (24 November 2004)

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Research article   Open Access

Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte

Aaron R Klooster, Suzanne M Bernier Arthritis Res Ther 2005, 7:R127-R138 (29 November 2004)

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Research article   Open Access

Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor κB-dependent pathway in patients with rheumatoid arthritis

Kyoung-Woon Kim, Mi-La Cho, Mi-Kyung Park, Chong-Hyeon Yoon, Sung-Hwan Park, Sang-Heon Lee, Ho-Youn Kim Arthritis Res Ther 2005, 7:R139-R148 (29 November 2004)

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Research article   Open Access

Circulating tumour necrosis factor-α bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical response

Hubert Marotte, Wlodzimierz Maslinski, Pierre Miossec Arthritis Res Ther 2005, 7:R149-R155 (1 December 2004)

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Research article   Open Access

Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading

Helga Lorenz, Wolfram Wenz, Mate Ivancic, Eric Steck, Wiltrud Richter Arthritis Res Ther 2005, 7:R156-R165 (7 December 2004)

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Research article   Open Access

JNK1 is not essential for TNF-mediated joint disease

Marcus Köller, Silvia Hayer, Kurt Redlich, Romeo Ricci, Jean-Pierre David, Günter Steiner, Josef S Smolen, Erwin F Wagner, Georg Schett Arthritis Res Ther 2005, 7:R166-R173 (7 December 2004)

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Research article   Open Access Highly Accessed

Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis

Uta Schurigt, Nadine Stopfel, Marion Hückel, Christina Pfirschke, Bernd Wiederanders, Rolf Bräuer Arthritis Res Ther 2005, 7:R174-R188 (10 December 2004)

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Correspondence

Letter   Free

Equipoise, design bias and randomized controlled trials: the elusive ethics of new drugs – a comment

Wolfgang Schimetta, Gabriele Poelz, Werner Poelz, Hans-Peter Haring, Franz Aichner Arthritis Res Ther 2005, 7:E2 (23 November 2004)

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Correspondence   Free

The 5th annual European League Against Rheumatism congress in Berlin: a personal perspective

Frank A Wollheim Arthritis Res Ther 2005, 7:E1 (1 December 2004)

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