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Volume 6 Issue 5

Comment

Viewpoint   Free

Biomarkers for systemic lupus erythematosus: has the right time finally arrived?

Barbara B Mittleman Arthritis Res Ther 2004, 6:223-224 (12 August 2004)

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Commentary   Free

The current status of targeting BAFF/BLyS for autoimmune diseases

Meera Ramanujam, Anne Davidson Arthritis Res Ther 2004, 6:197-202 (29 July 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review

Review   Free

Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients?

Fons AJ van de Loo, Ruben L Smeets, Wim B van den Berg Arthritis Res Ther 2004, 6:183-196 (29 July 2004)

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Review   Free

Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cells

P'ng Loke, James P Allison Arthritis Res Ther 2004, 6:208-214 (5 August 2004)

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Review   Free

Regulating the immune system: the induction of regulatory T cells in the periphery

Jane H Buckner, Steven F Ziegler Arthritis Res Ther 2004, 6:215-222 (11 August 2004)

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Review   Free

Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27

Alejandro V Villarino, Christopher A Hunter Arthritis Res Ther 2004, 6:225-233 (16 August 2004)

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Report

Meeting report   Free

Report on the Molecular Approaches to Osteoarthritis Symposium, Imperial College London, UK, 18–20 April 2004

Jeremy Saklatvala, Hideaki Nagase Arthritis Res Ther 2004, 6:203-207 (29 July 2004)

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Research

Research article   Open Access

Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes

Frédéric De Ceuninck, Audrey Caliez, Laurent Dassencourt, Philippe Anract, Pierre Renard Arthritis Res Ther 2004, 6:R393-R403 (28 June 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Disruption of binding between insulin-like growth factor 1 and IGF-binding proteins using a nonpeptide small molecule is shown to restore or enhance function in osteoarthritis chondrocytes in vivo.

Research article   Open Access

A proinflammatory role for Fas in joints of mice with collagen-induced arthritis

Hoang Tu-Rapp, André Hammermüller, Eilhard Mix, Hans-Jürgen Kreutzer, Roland Goerlich, Hansjürgen Köhler, Horst Nizze, Hans-Jürgen Thiesen, Saleh M Ibrahim Arthritis Res Ther 2004, 6:R404-R414 (19 July 2004)

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Research article   Open Access

Estrogen receptor-α gene haplotype is associated with primary knee osteoarthritis in Korean population

Sheng-Yu Jin, Seung-Jae Hong, Hyung In Yang, Sang-do Park, Myung-Chul Yoo, Hee Lee, Mee-Suk Hong, Hae-Jeong Park, Seo Yoon, Bum-Shik Kim, Sung-Vin Yim, Hun-Kuk Park, Joo-Ho Chung Arthritis Res Ther 2004, 6:R415-R421 (19 July 2004)

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Research article   Open Access

Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers

Stefan Fickert, Jörg Fiedler, Rolf E Brenner Arthritis Res Ther 2004, 6:R422-R432 (19 July 2004)

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Research article   Open Access Highly Accessed

Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease

Vera Sobek, Nico Birkner, Ingrid Falk, Andreas Würch, Carsten J Kirschning, Hermann Wagner, Reinhard Wallich, Marinus C Lamers, Markus M Simon Arthritis Res Ther 2004, 6:R433-R446 (19 July 2004)

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Research article   Open Access

Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate

Michele Bombardieri, Francesca Barone, Valerio Pittoni, Cristiano Alessandri, Paola Conigliaro, Mark C Blades, Roberta Priori, Iain B McInnes, Guido Valesini, Costantino Pitzalis Arthritis Res Ther 2004, 6:R447-R456 (3 August 2004)

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Hormone replacement therapy, calcium and vitamin D3 versus calcium and vitamin D3 alone decreases markers of cartilage and bone metabolism in rheumatoid arthritis: a randomized controlled trial [ISRCTN46523456]

Helena Forsblad d'Elia, Stephan Christgau, Lars-Åke Mattsson, Tore Saxne, Claes Ohlsson, Elisabeth Nordborg, Hans Carlsten Arthritis Res Ther 2004, 6:R457-R468 (6 August 2004)

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Research article   Open Access

Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model

Jarno van de Breevaart Bravenboer, Caroline D In der Maur, P Koen Bos, Louw Feenstra, Jan AN Verhaar, Harrie Weinans, Gerjo JVM van Osch Arthritis Res Ther 2004, 6:R469-R476 (6 August 2004)

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Research article   Open Access

Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis

Andrew D Cook, Robyn Gray, John Ramshaw, Ian R Mackay, Merrill J Rowley Arthritis Res Ther 2004, 6:R477-R483 (11 August 2004)

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Research article   Open Access

Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice

Ann-Sofie Hansson, Åsa CM Johansson, Rikard Holmdahl Arthritis Res Ther 2004, 6:R484-R491 (12 August 2004)

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