Research article

Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis

Fumiaki Kojima¹, Hiroaki Naraba², Satoshi Miyamoto³, Moroe Beppu³, Haruhito Aoki³ and Shinichi Kawai¹^*

¹ Institute of Medical Science, St Marianna University School of Medicine, Kawasaki, Japan

² National Cardiovascular Center Research Institute, Osaka, Japan

³ Department of Orthopedic Surgery, St Marianna University School of Medicine, Kawasaki, Japan

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Arthritis Res Ther 2004, 6:R355-R365 doi:10.1186/ar1195

Published: 8 June 2004