Arthritis Research & Therapy

official impact factor 4.36

Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies

Thomas Häupl*, Veit Krenn, Bruno Stuhlmüller, Andreas Radbruch and Gerd R Burmester

Arthritis Res Ther 2004, 6:140-146 doi:10.1186/ar1194

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Research article   Open Access Highly Accessed

Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration

Kristin Andreas, Thomas Häupl, Carsten Lübke, Jochen Ringe, Lars Morawietz, Anja Wachtel, Michael Sittinger, Christian Kaps Arthritis Research & Therapy 2009, 11:R15 (3 February 2009)

Research article   Open Access

Arthritis suppression by NADPH activation operates through an interferon-β pathway

Peter Olofsson, Annika Nerstedt, Malin Hultqvist, Elisabeth C Nilsson, Sofia Andersson, Anna Bergelin, Rikard Holmdahl BMC Biology 2007, 5:19 (9 May 2007)

In arthritis-susceptible rats, a natural alcohol, phytol, protects against arthritis by boosting NADPH oxidase via an interferon-beta associated pathway, in contrast to the interferon-gamma regulation of the immune system that drives arthritis progression.

Commentary   Free

Safety concerns on the development of novel therapeutic drugs

Caroline Ospelt, Steffen Gay Arthritis Research & Therapy 2006, 8:112 (1 September 2006)