Table 2

Spearman's rank correlations between anti-CRP levels (optical density) and SLEDAI, modified SLEDAI, serum levels of anti-DNA antibodies, complement components, CRP, and blood cell counts respectively

Analysis

BÅ

IS*

AR*

BB*

Total

Anti-CRP+

CRP

n.s.

< 0.05

n.s.

1/7

mSLEDAI

< 0.01

n.s.

< 0.05

< 0.01

< 0.02

n.s.

< 0.001

4/7

SLEDAI

< 0.002

n.s.

< 0.01

< 0.02

n.s.

< 0.001

3/7

C1q

n.s.

< 0.05

n.s.

< 0.05

n.s.

< 0.05

n.s.

< 0.002

2/7

n.s.

< 0.02

n.s.

< 0.005

1/7

n.s.

< 0.002

0/7

Platelet count

n.s.

< 0.05

n.s.

< 0.05

n.s.

2/7

White blood cell count

n.s.

< 0.05

< 0.02

n.s.

n.s

n.s.

2/7

Lymphocyte count

n.s.

< 0.02

< 0.05

n.s.

< 0.005

2/7

Anti-dsDNA (Farr)

< 0.002

n.s.

< 0.05

< 0.05

n.s.

< 0.01

n.s.

< 0.001

3/7

Anti-dsDNA (commercial ELISA)

< 0.002

n.s.

< 0.002

< 0.05

n.s.

< 0.05

< 0.01

4/7

Anti-dsDNA ('in-house' ELISA)

< 0.001

n.s.

< 0.02

n.s.

< 0.01

< 0.05

n.s.

< 0.001

4/7

Correlation in at least 1 variable

Yes

7/7

Results (P values) are presented at the individual level and for the whole patient material (n = 10). Positive correlations are given as bold P values and inverse correlations are shown in italics. The three consistently anti-CRP-negative cases are asterisked. In the last column, '4/7 anti-CRP+', for example, means that four of seven anti-CRP-positive patients had anti-CRP levels correlating to this particular variable. anti-CRP, anti-C-reactive protein autoantibody; CRP, C-reactive protein; mSLEDAI, modified systemic lupus erythematosus disease activity index; n.s., not significant; SLEDAI, systemic lupus erythematosus disease activity index.

Sjöwall et al. Arthritis Res Ther 2004 6:R87 doi:10.1186/ar1032