Table 1

Weight change after 9 weeks of treatment in female Sprague–Dawley rats (cohorts A and B) assessed in the studies of the effects of ovariectomy on cartilage

Weight (g)


Cohort

Treatment

Age at start (months)

n

Of body at start

Of body at end

Of uterus at end


A

OVX

5

10

292 ± 20

370 ± 28**

0.05 ± 0.02***

Shama

5

8

295 ± 28

324 ± 34

0.23 ± 0.03

B

OVX

7

9

327 ± 28

384 ± 24**

0.25 ± 0.20**

Shama

7

8

324 ± 29

342 ± 40

0.80 ± 0.45


Values are means ± SD. Difference between OVX and sham-operated rats were assessed using the nonparametric Mann-Whitney U test: aSham-operated. **P < 0.01, ***P < 0.001. OVX, ovariectomized.

Høegh-Andersen et al. Arthritis Res Ther 2004 6:R169-R180   doi:10.1186/ar1152

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