Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis

doi:10.1186/ar1027

Arthritis Res Ther

Volume 6
Issue 1

Viewing options:

Abstract
Full text
PDF (576KB)

Associated material:

Related literature:

Articles citing this article
on BioMed Central
on Google Scholar
on ISI Web of Science
on PubMed Central
Other articles by authors
on Google Scholar

Vossenaar ER
Zendman AJ
van Venrooij WJ

on PubMed

Vossenaar ER
Zendman AJ
van Venrooij WJ
Related articles/pages
on Google

on Google Scholar

on PubMed

Tools:

Post to:

Commentary

Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis

Erik R Vossenaar , Albert JW Zendman and Walther J van Venrooij

Department of Biochemistry, University of Nijmegen, The Netherlands

author email corresponding author email

Arthritis Res Ther 2004, 6:1-5doi:10.1186/ar1027


Published:	25 November 2003

Abstract

Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens.