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Commentary

SLE – Hematopoietic stem cell transplantation for systemic lupus erythematosus

Richard K Burt* and Ann E Traynor

Author Affiliations

Division of Immunotherapy, Northwestern University School of Medicine, Chicago, Illinois, USA

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Arthritis Res Ther 2003, 5:207-209  doi:10.1186/ar786

Published: 26 June 2003

Abstract

Hematopoietic stem cell transplantation was first reported for patients with systemic lupus erythematosus in 1997. The procedure has since been performed worldwide including in Europe, in Brazil, and in China. A National Institutes of Health-funded phase III clinical trial of hematopoietic stem cell transplantation for refractory systemic lupus erythematosus is anticipated to begin in 2003. Encouraging responses are raising new hope about the role of adult hematopoietic stem cells in systemic lupus erythematosus.

Keywords:
hematopoietic stem cell transplantation; lupus