Table 1

Frequency of CD4+CD28- T cells in control group and in patients with RA
Subjects
 CD4+CD28- T cells (%)a
 P
Control group
 1.40 (0.1–3.4)
Groups of RA patients

     1) With limited joint manifestations
 4.82 (3.71–10.95
 0.001b
     2) With advanced joint involvement
 7.05 (4.43–20.04)
 0.005c
     3) With extra-articular manifestations
 10.35 (4.19–36.60)
 0.001c

aMedian (range). bvs control group. cvs RA patients with limited joint manifestations.

Pawlik et al. Arthritis Res Ther 2003 5:R210   doi:10.1186/ar766