Table 1

Overall sensitivity and specificity of anti-centromere antibodies by indirect immunofluorescence in diagnosis of SSc

SSc versus:

Sensitivity (%)

Specificity (%)


Normal controls

33*

99.9*

Other connective tissue diseases

31*

95-97*

Primary Raynaud's phenomenon

24*

90*

Non-SSc relatives

19*

>99*


*Reference [35]. Reference [36].

Ho and Reveille Arthritis Res Ther 2003 5:80-93   doi:10.1186/ar628