Figure 1.

Schematic drawing of the known interactions between members of the TNF ligand family and members of the TNF/NGF receptor families. Death domains are indicated as black boxes (or gray boxes, in the cases of NGF-R and EDAR). EDAR, ectodysplasin-A receptor; NGF, nerve growth factor; NGF-R, receptor for nerve growth factor; TNF, tumor necrosis factor.