Genetic epidemiology: Psoriatic arthritis
Arthritis Rheumatism Campaign Epidemiology Research Unit, University of Manchester, UK
Arthritis Res 2002, 4:247-251 doi:10.1186/ar415Published: 31 January 2002
The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis. However, a distinct entity is likely to have distinct susceptibility factors in addition to those that contribute to psoriasis and inflammatory arthritis alone. These aetiological factors may be genetic and/or environmental, and in this review, the evidence for distinct psoriatic arthritis genetic susceptibility factors is considered.