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Review

Genetic epidemiology: Psoriatic arthritis

Anne C Barton

Author Affiliations

Arthritis Rheumatism Campaign Epidemiology Research Unit, University of Manchester, UK

Arthritis Res 2002, 4:247-251  doi:10.1186/ar415

Published: 31 January 2002

Abstract

The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis. However, a distinct entity is likely to have distinct susceptibility factors in addition to those that contribute to psoriasis and inflammatory arthritis alone. These aetiological factors may be genetic and/or environmental, and in this review, the evidence for distinct psoriatic arthritis genetic susceptibility factors is considered.

Keywords:
gene; genetics; psoriasis; psoriatic arthritis; review