Table 2

Expression of activation and differentiation markers on T cells (CD3+) from peripheral blood (PB) and synovial fluid (SF) of patients with juvenile idiopathic arthritis


CD4
CD8



Marker
PB
SF
PB
SF

CD69
2.8
9.1***
3.5
14.6***
CD25
3.7
6.0***
2.9
3.3*
CD71
2.8
5.0***
3.1
3.9**
HLA-DR
2.7
19.3***
3.5
26.7***
CD45RO
27.1
97.1***
23.6
73.9***
CD45RB
179.4
49.1***
273.8
142.0***

Values are median fluorescence intensity of the markers (except for CD45RO, which is expressed as % positive) on CD4+ or CD8+ T cells. *P < 0.05, **P < 0.01, ***P < 0.001, versus PB.

Black et al. Arthritis Res 2002 4:177   doi:10.1186/ar403